Clinical Trials & Research


Holy Cross Health has been a leader in orthopedic surgery for over 30 years. Holy Cross was one of the first hospitals in the country to pioneer surgical procedures such as total hip arthroplasty, robotic-assisted knee surgery, all arthroscopic rotator cuff repairs, arthroscopic hip surgery and reverse shoulder replacement. Holy Cross was the first in the world to perform MAKOplasty® - robotic assisted partial knee replacement. Our surgeons have developed patented devices and techniques that have facilitated major advancements in orthopedic surgery. In November 2010, Holy Cross Hospital reinvigorated its commitment to innovative orthopedics by launching the Orthopedic Research Institute.

Holy Cross Orthopedic Research Institute was founded with the intent of advancing the field of orthopedic surgery through high-quality research and education. The Orthopedic Research Institute continues the quest for excellence by focusing on clinical research, subspecialty fellowship and surgeon training, patient outreach education, and continuing medical education. These areas are fundamental for improving the diagnosis, treatment and care of all patients with musculoskeletal disorders.

Since the Orthopedic Research Institute’s inception in 2010, the clinical research department has rapidly expanded and now conducts orthopedic clinical trials in such sub-specialties as knee, hip, elbow, shoulder, interventional spine and pain medicine, and physical therapy. The Research Institute is dedicated to performing high-quality, ethically sound, scientifically meritorious clinical research that will advance orthopedic treatment and patient care. In the past 16 months, 17 peer-reviewed articles have been published from research conducted at the Holy Cross Orthopedic Research Institute. This amazing accomplishment is a testament to the high quality research being performed at our Institute. 

See our full list of current clinical trials.

Current and Past Research

  • Results of Robotic-Assisted Knee Replacement
  • Clinical Outcomes of Reverse Shoulder Replacement
  • Clinical Outcomes of Total Knee Arthroplasty using Sensor-Assisted Surgery
  • Clinical Outcomes of Surgical Treatment of Shoulder Fractures
  • Minimally invasive lumbar decompression for treatment of spinal stenosis
  • Peripheral nerve and spinal cord stimulation for pain management

Future Endeavors

As our dedication to orthopedic research grows, the future of the Holy Cross Orthopedic Research Institute includes:

  • Subspecialty Fellowship Training
  • Surgical Teaching Laboratory
  • Biomechanics Lab

Support our mission to deliver unsurpassed care.

As a non-for-profit entity, the Holy Cross Hospital Orthopedic Research Institute depends on the generosity of people like you to help maintain our mission to provide the absolute best treatment and our strong commitment to advancement in orthopedic surgery. With your support, we can continue to facilitate innovation in orthopedics though research and development and find ways to speed up recovery and minimize pain. Your generosity will also allow us to understand what it takes to improve joint and muscle function, and methods to get patients back to activities they enjoy.

To find out more about how you can help support orthopedic research, please call: 954-489-4579
All gifts donated are used in accordance with the donor's intent.